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Event Brief

I-40 East Shut Down After Serious 3-Vehicle Crash

A three-vehicle crash on Interstate 40 eastbound near the 360-mile marker at Buttermilk Road shut down all eastbound lanes Thursday evening around 6 p.m. Emergency crews treated patients ejected onto the roadway; two people were seriously injured and taken to UT Medical Center, including one airlifted by Lifestar. The Tennessee Highway Patrol is investigating the cause.
WHO: Tennessee Highway Patrol; emergency responders; Lifestar; Roane County Ambulance; University of Tennessee Medical Center
WHAT: Three-vehicle crash on I-40 eastbound near Buttermilk Road; eastbound lanes temporarily shut down; two serious injuries; patients treated on scene and transported to UT Medical Center
WHEN: Reported Aug 21, 2026 at 3:21 PM ET
WHERE: Interstate 40 near the 360-mile marker at Buttermilk Road, Knoxville, TN
WHY: Cause is under investigation by the Tennessee Highway Patrol.

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